Protein Tob1 (TOB1) (AA 61-91), (N-Term) Antikörper

Produktnummer ABIN453856

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch in WB, IHC (p), FACS und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Protein Tob1 (TOB1) (AA 61-91), (N-Term) Antikörper (ABIN453856)

Target: Protein Tob1 (TOB1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails

Bindungsspezifität: AA 61-91, N-Term

Spezifität: This antibody recognizes TOB1 (N-term).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 61~91 amino acids from the N-terminal region of Human TOB1 Genename: TOB1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Antigendetails

Target: Protein Tob1 (TOB1)

Andere Bezeichnung: TOB1

Hintergrund: TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.Synonyms: TOB, TROB1, Transducer of erbB-2 1

Gen-ID: 10140

NCBI Accession: NP_005740

UniProt: P50616